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Skin Cancer

From Mole to Melanoma: Skin Cancer Explained


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Summary & Participants

More and more Americans are diagnosed with melanoma every year -- among them Senator John McCain, who was originally diagnosed in 1993. This year will bring approximately 47,000 new cases, many due to excess sun exposure, and some 7,700 people will die from the disease. What is melanoma, and what can you do to prevent it? Join our panel of experts as they discuss this and other cancers of the skin.

Medically Reviewed On: May 07, 2008

Webcast Transcript


MARTY MOSS-COANE: I'm Marty Moss-Coane. Welcome to our webcast. A generation ago, skin cancer was rarely discussed, and was a problem mainly for older people. Today, the threat and reality of skin cancer has become front page news. There has been a dramatic increase in the number of people who are getting treated for cancers of the skin. In fact, skin cancer is the most common cancer that doctors see. Melanoma, in particular, can be deadly if unnoticed and untreated, especially in the later stages.

Today in our webcast, we'll discuss how to identify melanoma and what you can do to protect yourself against the harmful rays of the sun.

Joining us are Dr. David Leffell, a Professor of Dermatology and Surgery at Yale School of Medicine, and the author of "Total Skin" which is published by Hyperion. Dr. Leffell, welcome.

DAVID J. LEFFELL, MD: Thank you.

MARTY MOSS-COANE: Nice to have you here. Dr. Arielle Kauvar is a dermatologist, Professor of Dermatology at NYU Medical Center, and Vice President of the Dermatology Society of Greater New York. Dr. Kauvar, welcome to you as well.

ARIELLE KAUVAR, MD: Thank you.

MARTY MOSS-COANE: Let's put some definitions on the table. To you, Dr. Leffell, what is melanoma? Describe that for us please.

DAVID J. LEFFELL, MD: Melanoma is a skin cancer that originates in the pigment-producing cell that exists in the top layer of the skin. It's a cancer that is potentially lethal. But the good news is that if identified early, it can be treated in a simple office procedure, and the cure rate is extremely high.

MARTY MOSS-COANE: In just a second or two, we'll be putting up some pictures so that our audience can really see what it is that melanoma looks like. I think it's still important for some other words for the audience to be familiar with melanoma compared to what other kinds of skin cancer.

DAVID J. LEFFELL, MD: There are really two additional types of skin cancer; basal cell cancer and squamous cell cancer. Together, these are actually the most common types of skin cancer, and the ones that are most likely due to exposure to the sun. Melanoma can result from sun exposure as well, but there are certainly melanomas that develop where the sun doesn't shine. So I think in order to better understand skin cancer, it might make sense to take a look at some examples of each of these forms of skin cancer.

MARTY MOSS-COANE: Let's do that, and then we can talk about it as we look at some of the pictures, which we will be putting up on the screen in just a second.

Why don't you describe to us what we're looking at right now?

DAVID J. LEFFELL, MD: You're looking at a mole that's about a third of an inch in diameter. It's got irregular pigmentation. It's got different shades of brown and tan in it. Importantly, the edges are irregular. You can see that it's not symmetric. These are all signs of a melanoma while it's in the horizontal, or spreading phase.

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